Mannitol 10% kan worden gebruikt:
- Bij een acute nierinsufficiëntie om oligurie te voorkomen of te behandelen vóór nierbeschadiging optreedt
- Om de intracraniële druk te verminderen of om cerebraal oedeem te behandelen
- Ter vermindering van de intraoculaire druk of tijdens oogoperatie
- Bij vergiftigingen omm de excretie van toxische bestanddelen via de urine te bevorderen
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